Rugiet Health | Frequently Asked Questions

Medical

How does Rugiet Ready work?

Rugiet Ready contains a class of medications called PDE5 inhibitors, which work by dilating blood vessels and increasing blood flow to the penis, making it easier to get and maintain an erection. It also includes APO, (apomorphine) a dopamine promoter, which primes the brain for sexual arousal.

What is Rugiet Ready's mechanism of action?

An erection is a physiological response in which the penis becomes rigid and enlarged due to increased blood flow. This response is triggered by sexual stimulation, which induces the release of a vasodilator molecule called nitric oxide. Nitric oxide activates an enzyme that catalyzes the conversion of GTP to cGMP, a molecule that leads to smooth muscle relaxation and blood vessel dilation, increasing blood flow into the penis and resulting in an erection.
Phosphodiesterases are the group of enzymes in the body responsible for breaking down cGMP. Two of the medications in Rugiet Ready, sildenafil and tadalafil, are phosphodiesterase type 5 (PDE5) inhibitors. Inhibiting PDE5 increases the amount of available cGMP, which in turn increases smooth muscle relaxation and blood vessel dilation, increasing overall blood flow into the penis and resulting in an erection.
Apomorphine, the third ingredient in Rugiet Ready, is a dopamine promoter that acts on dopamine receptors in the brain. It primes the parts of the brain associated with sexual arousal, strengthening the signal that links sexual stimulation and the erection cascade.

How long do the effects of Rugiet Ready last?

The effects of sildenafil generally last 4-5 hours, while the effects of tadalafil typically last for 24-36 hours. Using this medication with liver or kidney disease may increase the time that this medication remains in the body and we recommend consulting with your doctor prior to use. Concurrent use of certain medication may also prolong the effects or cause adverse effects. Please see the below question regarding medication interactions. Apomorphine generally lasts 3-4 hours.

What are the most common side effects?

Headache
Flushing
Rash
Cyanopsia (blue-tinted vision)
Mild blurred vision
Indigestion
Irritation of the skin within the mouth and under the tongue
Nasal Congestion
Nausea
Back Pain
Muscle pain (myalgia)
Dizziness
Drowsiness

What symptoms are serious enough where I should seek medical attention immediately?

Chest pain
Dizziness or Syncope (fainting)
An erection lasting longer than four hours
Any sudden changes in hearing or vision
Allergic Reaction (swelling of the face and lips, wheezing, sensation of throat closing, difficulty breathing, rash)
Serious Skin Reactions (rashes, blistering, peeling)

Can I take Rugiet Ready with other medications?

Rugiet Ready can interact with other medications you may be taking. Make sure to be honest and thorough with your doctor during the medical survey to avoid any adverse effects.
Medications containing any nitrates (such as nitroglycerin, isosorbide mononitrate or isosorbide dinitrate), nitrites or alkyl nitrites (also known as “poppers” or “rush”), as well as guanylate cyclase (GC) stimulators (such as riociguat or Adempas) must NOT be used at the same time as Rugiet Ready, as this combination may lead to a dangerous drop in blood pressure and/or syncope (fainting).
Revatio (sildenafil) is a medication prescribed for pulmonary hypertension. Do not take Rugiet Ready if you are prescribed Revatio (sildenafil)
Do not take with any illegal drugs.
AVOID grapefruit, grapefruit juice and excessive alcohol consumption when taking Rugiet Ready.
Use caution when taking Rugiet Ready with alpha-blockers or anti-hypertensive (blood pressure) medications, as this may lead to a drop in blood pressure and/or syncope (fainting).
Use caution when taking Rugiet Ready with strong CYP inhibitors (such as ritonavir, saquinavir, ketoconazole, itraconazole, erythromycin), as Rugiet Ready metabolism is decreased, and this may lead to a prolonged erection, a drop in blood pressure and/or syncope (fainting).
Rugiet Ready can interact with the following commonly prescribed medications. This is not an all-inclusive list. Be sure to include all medications that you take in the patient survey. If your medication list changes be sure to message your doctor.

Nitrate-containing medication
nitroglycerin (Gonitro, Nitrolingual, NitroMist, Nitrostat)
isosorbide mononitrade (Imdur, Ismo, Monoket)
isosorbite dinitrate (Dilatrate-SR, Isordil, Isordil Titradose)
nitrites or alkyl nitrites known as “poppers” or “rush”
Revatio (sildenafil)
Guanocyclase stimulators
riociguat (Adempas)
Alpha blockers
alfuzasin (Uroxatral)
doxazosin (Cadura)
dutasteride and tamulosin (Jalyn)
prazosin (Minipress)
silodosin (Rapaflo)
riociguat (Adempas)
terazosin (Hytrin)
Protease inhibitors
atazanavir (Reyataz)
darunavir (Prezista)
fosamprenavir (Lexiva)
indinavir (Crixivan)
lopinavir/ritonavir (Kaletra)
nelfinavir (Viracept)
ritonavir (Norvir)
saquinavir (Invirase)
tipranavir (Aptivus)
atazanavir/cobicistat (Evotaz)
darunavir/cobicistat (Prezcobix)
Antifungal medications
ketoconazole (Nizoral)
itraconazole (Sporanox)
Antibiotics
clarithromycin (Biaxin)
telithromycin (Ketek)
fosamprenavir (Lexiva)

All blood pressure medications can potentially cause a drop in blood pressure when used with Rugiet Ready and should be included in your medication list.

What if I have other medical conditions?

There are many people with other medical conditions that have successfully treated their E.D. with Rugiet Ready. However, your doctor will review all the information that you provide in your health questionnaire before determining if Rugiet Ready is right for you. It is important that you are detailed and honest in your responses. If you have questions about your medical history, please consult your primary care physician. Your Rugiet Ready doctor will reach out to you for more information before prescribing if required.

Is it safe take sildenafil and tadalafil together?

Sildenafil and tadalafil can safely be combined so long as they are prescribed by a licensed physician who has thoroughly reviewed your medical history and can be contacted to modify your dosage if needed. To learn more about decision to combine these ingredients, read this article here.

Can I take Rugiet Ready while drinking alcohol?

Our doctors recommend you do not take Rugiet Ready when you will be drinking heavily.

Can I take Rugiet Ready while using illicit drugs?

Our doctors recommend you do not take Rugiet Ready while engaging in illicit drug usage.

Can I smoke/vape while taking Rugiet Ready?

Our doctors recommend you wait at least 30 minutes after taking Rugiet Ready to smoke or vape. This is because smoking may affect the absorption of the medication.

Will Rugiet Ready help me last longer? Can it help me “go again”?

Rugiet Ready contains two PDE5 inhibitors, which have been shown in studies to be an effective treatment for premature ejaculation. It may also help decrease the amount of time it takes for you to obtain subsequent erections.

Does Rugiet Ready increase sensitivity?

Rugiet Ready can help you get and maintain an erection. A strong erection can help increase sensitivity. However, the product itself does not affect sensitivity of the penis.

Will Rugiet Ready get me hard?

Rugiet Ready can help you initiate and maintain an erection. This is because the medication works to dilate blood vessels which will cause more blood flowing into the penis.

If Viagra® and Cialis® didn’t work for me, will Rugiet Ready?

There are many people who successfully treated their E.D. with Rugiet Ready after trying single-ingredient treatments, like Viagra® and Cialis®, did not yield results. Rugiet Ready combines both sildenafil and tadalafil, which are short and long acting PDE5 inhibitors. It also includes a third ingredient, apomorphine. Because the medication dissolves under the tongue, it increases absorption directly into the bloodstream, making it work faster. Furthermore, our physicians can customize doses of each medication specifically to each patient’s need. We cannot promise it will work for everyone, but our doctors will work with you to try to deliver optimal results while minimizing side effects. Read more about your options here.

I take a low dose of tadalafil every day, can I take Rugiet Ready every day?

No, Rugiet Ready is not a daily medication. It should only be taken as needed per the instructions on your prescription. The maximum recommended dosing frequency of Rugiet Ready is one dose in every 24 hours.
For Rugiet Ready combinations that contain greater than 10mg of tadalafil, it should be noted that tadalafil can stay in the bloodstream for up to 36 hours, and this should be taken into consideration.

I have taken Viagra®/Cialis® before and I have experienced side effects. Will I experience the same side effects with Rugiet Ready?

Rugiet Ready contains the same active ingredients as both Viagra® and Cialis®, so you may experience similar side effects. However, our doctors will work with you to try to find the best treatment and dosage to help limit side effects while maintaining effectiveness. It's often reported that side effects are minimized and even eliminated thanks to the custom doses.
Be sure to explain to your doctor in the questionnaire if you had previous side effects or drug reactions using Viagra® or Cialis®. If you have any other questions do not hesitate to message your doctor. Read more about how Rugiet Ready is different here.

What strength should I choose?

Our product selection page will provide you with some general advice to help get you started. Your doctor will review your request in the context of your answers to the medical questionnaire and only approve it if they feel it is a safe and effective treatment option for you. We recommend starting with half a dose and increasing to a full dose if needed. You can message your Rugiet Ready doctor to increase your dose if the full dose is not producing desirable results. If our physicians require more information, they will contact you through the Member Portal or via the email you provided during sign up.

What is apomorphine?

Apomorphine is a dopamine promoter. It activates the dopamine receptors in the brain to create erections by priming the brain for sexual arousal. Contrary to its name, apomorphine does not actually contain morphine or in any way have similar effects or uses. Other uses include as a treatment for Parkinson’s Disease. May cause drowsiness.

Can females use Rugiet Ready?

No, Rugiet Ready is not intended for female use.

Will Rugiet Ready prevent pregnancy or protect me from sexually transmitted infections?

No, Rugiet Ready will not prevent pregnancy or protect from sexually transmitted infections.

What are other things that I can do to improve my sexual function?

Rugiet Ready works by increasing blood flow to the penis and thus increasing the ability to obtain and maintain an erection. Increasing overall health and wellbeing can also improve sexual function.
This includes maintaining a healthy body weight, exercising, and quitting smoking. Maintaining control of medical conditions such as high blood pressure and diabetes can also improve sexual function.
Although we do not treat these diseases at Rugiet Health, we recommend working closely with your primary care physician to optimize your overall health and thus improve your sexual function.

Product

What is Rugiet Ready?

Rugiet Ready is a fast-acting, long-lasting E.D. medication combining sildenafil and tadalafil, the active ingredients in Viagra® and Cialis®, with apomorphine, a dopamine promoter that primes the brain for arousal. Rugiet Ready dissolves under your tongue, bypassing your stomach and liver, which creates a fast onset.

Rugiet Ready contains the same active ingredients as Viagra® and Cialis®, but you claim that it works faster. How is that possible?

Rugiet Ready works faster than Viagra®/Cialis® pills & chewable tablets because it comes in dose designed to absorb under the tongue (also known as a sublingual troche). This allows the medication to be absorbed directly into your bloodstream as opposed to having to pass through your digestive system. Read more about how Rugiet Ready is different here.

What does Rugiet Ready taste like?

Rugiet Ready has a tasty mint-chocolate flavor.

How long does Rugiet Ready take to dissolve?

For most men, Rugiet Ready takes about 5-10 minutes to dissolve.

If Rugiet Ready doesn’t work for me, can I get my money back?

Because Rugiet Ready is a prescription medication that is custom made for each patient, it is non-refundable.
If you are unhappy with the product, or have any questions or concerns at all, our concierge Customer Care team will be happy to assist you during our business hours: 8am-6pm CT Mon-Fri
For the fastest response time, chat with us by logging into your secure Members Portal.
You can email us at customercare@rugiet.com, or reach us by phone at (855) 581-9620.

Why isn’t my medication bright blue?

The blue square seen in our pictures does not contain any medication, which leaves it a bright blue color. Once the medications are added, it changes the color of the finished product (varying from light to dark green). The green medication is safe to take.

How long has Rugiet Ready been on the market?

Rugiet Ready was developed over 6+ years of research and development and launched under the Rugiet Health brand in 2020.
Learn more about our story in our blog.

What are the inactive ingredients in Rugiet Ready?

Rugiet Ready contains the following inactive ingredients:

spearmint flavoring
chocolate flavoring
vanilla flavoring
marshmallow flavoring
menthol
steviol glycosides
acesulfame potassium
gum acacia
silica
polyethylene glycol
bitterness reducing agent
blue food coloring

How do you ensure the quality and safety of your medication?

We partner exclusively with licensed compounding pharmacies that maintain the highest standards in pharmaceutical preparation. Through regular audits and routine batch testing, our pharmacy partners verify that every medication meets our strict quality requirements. This rigorous oversight ensures all formulations are tested and certified to meet industry-standard accuracy specifications, so you can have confidence in the safety and effectiveness of your treatment.

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Ordering

How do I order Rugiet Ready?

Ordering Rugiet Ready is easy and secure:
Before you begin, please have the names of any medications you are taking and a valid government-issued photo ID ready. Then, follow the steps below.

Go to www.www.rugiet.com.
Click 'Customize Your Treatment.'
Complete the online medical questionnaire so one of our board-certified doctors in the Rugiet Health network can evaluate and determine if Rugiet Ready is right for you.

How long does it take to receive my order?

Rugiet Ready ships within 48 hours after your order is processed, depending on the day you order.
New Members: The doctor will take up to 24 hours to prescribe before processing. The process may take slightly longer if the doctor has any follow-up questions.
Florida Residents: We ship Mon-Thurs. Shipping on Friday is possible if UPS offers Saturday delivery to your area.
All Other States: We ship Mon-Wed. Thursdays are possible if UPS offers Saturday delivery to your area.
Note: If you are expecting a Saturday delivery, but UPS is unable to fulfill it, you will receive your order on Monday.

Will a doctor contact me?

A doctor will review your health questionnaire and requested dose strength within 24 hours of placing your order. If your doctor requires additional information, you will be contacted through the Member Portal or via the email you provided during sign up.
*Please note, your order may be delayed until your doctor receives all necessary information to authorize your prescription.

How do I know the date of my next refill?

Log into your Member Portal and select “ORDERS.” See the date of your last order, and your next autofill will be processed 48 hours before the next due date.
Example: if your last order was on 01/15/2023, your next autofill will be processed on 02/13/2023 (48 hours before the refill due date of 02/15/2023)

Can I pay with insurance?

Rugiet Ready is a compounded medication. Compounded medications are not covered by medical insurance. However, it is possible to pay with an FSA or HSA card if your provider deems Rugiet Ready a covered medical expense.

Membership

Is Rugiet Ready a subscription service?

Rugiet Ready offers different Membership Plans that can save you money if you choose to order regularly. You can pause your Membership Plan anytime through your Member Portal. Rugiet Ready also offers a one-time purchase option available at checkout. You can opt into a Membership Plan anytime you want.

How do I update my payment information?

Log into your Member Portal and select the “Edit Profile” option to view past orders, order status, and payment.

How much does Rugiet Ready cost?

The price of Rugiet Ready depends on your selection of dosage strength, number of packs, and delivery option. Each strength comes in a pack that contains 6 doses.

Max Strength - $24/dose

Most Prescribed - $20/dose

Medium Strength - $17/dose

Low Strength - $14/dose

The best way to know your grand total is to complete the online medical questionnaire, where you may be eligible for instant savings. Doses can be as low as $10/dose.

How do I place a new order?

Log into your Member Portal and select the “Order Now” option.

Can I get a refund?

If you would like to learn more about our Refund Policy, click here.

How do I cancel my order?

To cancel your order before the doctor has begun the consultation, login to the Members Portal and click ‘Cancel Order’. If the doctor has already begun or finished the consultation, please contact Customer Care. The order cannot be cancelled once the medication is made, so please act promptly.
Contact Customer Care: 1(855) 581-9620
8am – 6pm CT Mon-Fri

Shipping

Is Rugiet Ready available in my state?

Rugiet Ready is available in all 50 states.

How long does it take to receive my order?

Rugiet Ready ships within 48 hours after your order is processed, depending on the day you order.
New Members: The doctor will take up to 24 hours to prescribe before processing. The process may take slightly longer if the doctor has follow-up questions.
Florida Residents: We ship Mon-Thurs. Shipping on Friday is possible if UPS offers Saturday delivery to your area.
All Other States: We ship Mon-Wed. Thursdays are possible if UPS offers Saturday delivery to your area.
Note: If you are expecting a Saturday delivery, but UPS is unable to fulfill it, you will receive your order on Monday.

What shipping courier do you use?

Rugiet Ready uses UPS Ground for Florida, UPS Air for the other mainland states, and FedEx for Hawaii.

How do I receive tracking information for my shipment?

An email is sent to you once the tracking number is created.
Don’t see the email?
Check your spam/junk folder. Sometimes it mistakenly lands there due to the nature of the product.

Do you use discreet packaging?

Your order will arrive in a UPS branded Express Box with the name of the pharmacy on the label. There is no Rugiet Ready branding on the shipping packaging.

How do I change/correct my delivery address while my order is in transit?

To redirect your package, go into the tracking reference. Then select and register with UPS Choice. Once registered with UPS Choice and logged in, there will be an option to redirect.

What do I do if there's a problem with my order?

Our concierge customer care team will be happy to assist you during our business hours: 8am-6pm CT Mon-Fri
For the fastest response time, chat with us by logging into your secure Member's Portal.
You can email us at customercare@rugiet.com, or reach us by phone at (855) 581-9620.

Packaging/Storage

My order came with ice packs, do I need to freeze it?

Your order may be shipped with ice packs to keep the medication at or below room temperature during transit. Once you receive the package, store it at room temperature or refrigerate/freeze it if the product appears partially melted. Melting and freezing do not alter the ingredients of the medication.

My Rugiet Ready arrived melted, what do I do?

Rugiet Ready comes in the form of a sublingual troche, a dose designed to melt under your tongue at body temperature. During summer months, ambient temperatures sometimes exceed 95°F, which can cause the medication to melt slightly during transit.
In warmer months, we take precautions against this by shipping the medication with ice packs and in a thermal sleeve - but still - in inclement weather, it is possible your medication may arrive melted.
If your Rugiet Ready arrived melted, do not open it. Place it in the refrigerator. The medicine is good to use once it has solidified in its blister package.
If this does not work or you have any questions, our concierge Customer Care team will be happy to assist you during our business hours: 8am-6pm CT Mon-Fri
For the fastest response time, chat with us by logging into your secure Member's Portal.
You can email us at customercare@rugiet.com, or reach us by phone at (855) 581-9620.

How do I store Rugiet Ready?

Rugiet Ready should be stored in a cool, dry place at room temperature (74°F) or below. We sometimes ship with ice to maintain the quality of the product in transit to warmer places.

Technical Problems

Having trouble logging into your account?

Go to your Member's Portal.
Check that you are entering the correct email and password.
Reset your password by selecting Forgot Password, and following the steps listed.

If this does not work, try the following:

Clear the cache in your browser or delete your browsing history and try again. See the links below for how
Try to log in from a different browser or a different device.

If these suggestions do not work, for the fastest response time, you can chat with us 8am-6pm CT Mon-Fri by logging into your secure Member's Portal here.

You can email us at customercare@rugiet.com, or reach us by phone at (855) 581-9620.

FREQUENTLY ASKED QUESTIONS